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OBJECTIVE:To strengthen the management and risk control of 4 kinds of special drugs in pharmacy intravenous admixture service(PIVAS),and promote the drug use safety. METHODS:The 4 kinds of special drugs(high-alert drugs,hazard-ous drugs,important drugs/costly drugs and drugs needed for skin allergy test)in PIVAS were precisely managed by classification. The effect evaluation was carried out by tracer methodology. RESULTS:The 4 kinds of drugs were classified and managed by de-veloping specified directory,mading special logo,fixing position storage,strengthening medical order review,establishing emer-gency plan,daily inventory,batch number management,etc. It had standardized the management and use process of high-alert drugs,ensured the operational safety for hazardous drug and occupational protection,made the compliance rate reached 100% of important drugs/costly drugs,and ensured the consistency of preparation and use batch number of drug for skin allergy test basical-ly. Compared with before management(2015),the items ratio achieving good level(class B)and above in 18 evaluation indicators had increased from 22.23% to 94.44% after management (2016). CONCLUSIONS:The precise management by classification in PIVAS of our hospital has better controlled the management and risk of 4 kinds of special drugs in clinical use,and ensured the safe operation of PIVAS.
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Objective To study the effects of compound rhizoma bletillae paint (CRBP) on scalded rats. Methods Rats were randomly divided into test groups (CRBP low, high dose group), CRBP-CA (CRBP without chlorhexidine acetate) group, positive control group (Jingwanhong) and negative control group (no treatment) respectively, with 10 rats in each group. The drugs were administered topically on the surface of scalded places respectively after second-degree and third-degree burn scald models in rats. The rats were bred separately. The scabbing time, decrustation time and wound healing time were recorded. Results The scabbed and the decrustation time were shorter in the test group than that in the negative control group with significant differences (P
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OBJECTIVE:To establish the quality standard of Baoshenling capsules.METHODS:Radix Astragali,Radix et Rhizoma Rhei,Ligusticum chuanxiong and Hirudo were identified qualitatively by TLC,and the content of diphenyl ethylene in Baoshenling capsules was determined by HPLC.RESULTS:The characteristic TLC spots of Radix Astragali,Radix et Rhizoma Rhei,Ligusticum chuanxiong and Hirudo were identified accurately.The linear range of diphenyl ethylene was 0.176～0.880?g(r = 0.999 8) with an average recovery rate of 98.9%(RSD = 1.3%,n =6).CONCLUSION:The established standard is applicable for the quality control of Baoshenling capsules.